Quantitative confirmation of testosterone and epitestosterone in human urine by LC/Q‐ToF mass spectrometry for doping control
نویسندگان
چکیده
منابع مشابه
Detection of epitestosterone doping by isotope ratio mass spectrometry.
BACKGROUND Epitestosterone is prohibited by sport authorities because its administration will lower the urinary testosterone/epitestosterone ratio, a marker of testosterone administration. A definitive method for detecting epitestosterone administration is needed. METHODS We developed a gas chromatography-combustion-isotope ratio mass spectrometry method for measuring the delta(13)C values fo...
متن کاملDevelopment and method validation for testosterone and epitestosterone in human urine samples by liquid chromatography applications.
An isocratic high-performance liquid chromatographic method for the determination of testosterone (T) and epitestosterone (ET) in human urine using liquid-liquid or solid-phase extraction (SPE) is developed and validated. The optimum separation is achieved using a Hypersil C(18) column, water-acetonitrile (57:43, v/v) as the mobile phase and UV-absorbance detection at 245 nm. The recoveries obt...
متن کاملStability studies of testosterone and epitestosterone glucuronides in urine.
The stability of testosterone glucuronide (TG), epitestosterone glucuronide (EG) and the T/E ratio in urine has been studied. Samples were analyzed by gas chromatography coupled to mass spectrometry (GC/MS). Urine samples were submitted to a solid-liquid cleanup followed by extraction of unconjugated testosterone (T) and epitestosterone (E) with tert-butyl methyl ether (free fraction). The rema...
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in the area of automotive engineering there is a tendency to more electrification of power train. in this work control of an induction machine for the application of electric vehicle is investigated. through the changing operating point of the machine, adapting the rotor magnetization current seems to be useful to increase the machines efficiency. in the literature there are many approaches wh...
15 صفحه اولQuantitative analysis of mitragynine in human urine by high performance liquid chromatography-tandem mass spectrometry.
Mitragynine is the primary active alkaloid extracted from the leaves of Mitragyna speciosa Korth, a plant that originates in South-East Asia and is commonly known as kratom in Thailand. Kratom has been used for many centuries for their medicinal and psychoactive qualities, which are comparable to that of opiate-based drugs. Kratom abuse can lead to a detectable content of mitragynine residue in...
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ژورنال
عنوان ژورنال: Journal of Mass Spectrometry
سال: 2008
ISSN: 1076-5174,1096-9888
DOI: 10.1002/jms.1443